✂️ CutSeq

Trim sequencing adapters in a correct way.

Get started View on GitHub


Why CutSeq?

NGS library preparation can require many sequential trimming and extraction steps. For example, the SMARTer® Stranded Total RNA-Seq Kit v3 workflow needs at least 9 operations, including adapter removal, UMI extraction, linker masking, and poly-A/T trimming. CutSeq automates these steps in the correct order, reducing errors and saving time.

Key Features

  • Single-parameter trimming: Specify your library scheme with one parameter.
  • Built-in and custom adapters: Use a preset or define your own scheme.
  • Efficient and reproducible: Avoids multiple I/O steps and manual errors.

CutSeq is open source and welcomes contributions! See the GitHub repo for details.

Quick Navigation


Copyright © 2021-2024, Chang Ye